Essas são pelo menos as mais conhecidas. Vou explora-las no curso de Métodos Computacionais. (Boa ideia):
Axelrod: a research library aimed at the study of the Iterated Prisoners dilemma.
Gambit: a C library with a Python interface for the computation of equilibria
Game theory explorer a web interface to gambit useful for teaching.
PyNFG: PyNFG is a Python package for modeling and solving Network Form Games.
lrslib: A C implementation of a reverse search algorithm with modules for Nash equilibria computation.
sagemath: The mathematical software package Sage has various algorithms for the computation of Nash equilibria.